Before an embryo is transferred, a few cells are biopsied and screened — for chromosome number (PGT-A), for a known familial mutation (PGT-M), or for structural rearrangements (PGT-SR). China's PGT programmes are licensed and large-scale, and for families carrying hereditary disease, PGT-M means having a healthy child without rolling genetic dice.
| Option | Best suited for | What it means in practice |
|---|---|---|
| PGT-M (monogenic) | Known familial mutations | Custom probe design; works for rare variants — feasibility answered before you pay. |
| PGT-A (aneuploidy) | Age-related risk, recurrent loss | Euploid-only transfer lowers miscarriage substantially. |
| PGT-SR (structural rearrangements) | Translocation carriers | Balanced-embryo selection. |
| Typical China cost (reference only) | US$1,500–3,000 on top of the IVF cycle cost (PGT-M test design can add more for rare mutations) |
|---|---|
| Typical in-hospital stay | Outpatient; embryo transfer happens weeks after biopsy results |
| Return-to-travel timeline | Two trips: ~2 weeks for retrieval + biopsy, then ~1 week for the frozen transfer (or stay between) |
Costs are indicative ranges for international self-pay patients at major Chinese hospitals; final quotes depend on the hospital, implant/medication choice and case complexity. WellVoyage locks a written all-in quote before you commit.
She and her husband are both carriers of the same gene. PGT-M in Guangzhou tested embryos for their exact variants; the transferred embryo is a carrier of neither, and their son breathes easily.
Five miscarriages before karyotyping found the rearrangement. PGT-SR in China selected a balanced embryo; the pregnancy that followed is her longest, and it ended in a delivery.
Repeated early losses and a home clinic offering sympathy. PGT-A in Shanghai showed most of their embryos were aneuploid — an answer, not a comfort, but the first euploid transfer stuck.
Both carriers of the same haemoglobinopathy. PGT-M in Beijing tested embryos for the family's specific mutation; their daughter was born free of the disease their extended family knows too well.
A prior trisomic loss made every subsequent positive test a vigil. PGT-A in China let her transfer a tested euploid embryo; the nine months that followed were anxious, but ordinary-anxious.
At 38 the arithmetic of chromosomes turns unfriendly. PGT-A in Guangzhou screened her batch; two euploid embryos from four biopsied, and the first transfer succeeded.
A rare familial condition in her family tree. Pre-test work-up in China built a custom PGT-M assay for the family variant; their embryo was tested negative for it.
It dramatically lowers — not eliminates — the tested risks. PGT-A reduces miscarriage from aneuploidy; PGT-M prevents the tested familial disease. Prenatal testing in pregnancy remains standard practice, and the Chinese counselling sessions say so explicitly.
Usually yes: PGT-M test design (haplotyping) works for rare variants, and Chinese PGT labs handle unusual cases routinely. Send your family's genetic reports — the lab's feasibility answer comes back before you pay anything.
WellVoyage translates your records, obtains independent specialist opinions, and locks a transparent written quote — before you book a flight.
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